I don't really know how to compare it to other multiplexed base editing methods; this article says it reduces "crosstalk", https://www.sciencedaily.com/releases/2024/05/240521124304.htm unwanted edits due to multiple RNAs interacting. without being deep into this field I just assume there's a lot of different methods out there and I don't (yet) feel prepared to pick a winner.
Hi Sarah,
What are your thoughts on GeneSmith's adult-brain intelligence enhancement proposal?
I.e.: https://www.lesswrong.com/posts/JEhW3HDMKzekDShva/significantly-enhancing-adult-intelligence-with-gene-editing
Typo: 229%, the abstract spoke of 228% increase in yield.
Thanks for this wonderful overview, Sarah.
Any thoughts on MOBE (multiplexed orthogonal base editors) - useful new approach or variation on a theme?
I don't really know how to compare it to other multiplexed base editing methods; this article says it reduces "crosstalk", https://www.sciencedaily.com/releases/2024/05/240521124304.htm unwanted edits due to multiple RNAs interacting. without being deep into this field I just assume there's a lot of different methods out there and I don't (yet) feel prepared to pick a winner.